Created by the International Society of Automation (ISA), the ISA Global Cybersecurity Alliance looks to leverage the ISA/IEC 62443 standards and expand cybersecurity expertise. THis way, they can openly share knowledge and resources and protect the OT cybersecurity worldwide community.
DeNexus delivers an evidence-based solution for OT industrial stakeholders. The goals is to gain visibility into each facility’s cyber exposure. Then they can calculate the probability and financial impact of potential cyber incidents and prioritize risk mitigation based on ROI or other KPIs.
DeNexus founder and chief executive Jose M. Seara spoke at the ISA OT Cybersecurity Summit in Prague in June 2026. His session focused on “OT Cyber Insurance and Risk Transfer: Right-Sizing Coverage Using Evidence, Not Guesswork.”
Through ISAGCA membership, DeNexus will collaborate with global industry leaders. The goal is to accelerate awareness, adoption and implementation of the ISA/IEC 62443 standards framework.
“This is a significant moment for the ISAGCA community,” said Michelle Ritterskamp, ISAGCA program coordinator. “DeNexus brings a deep OT technical experience and a desire to incorporate ISA/IEC 62443 into their business.”
“Industrial cyber risk has been invisible to the people who carry it – boards, CFOs and the markets that could underwrite it,” Seara said. “That’s the problem I started DeNexus to solve, and it’s the same problem ISA/IEC 62443 addresses from the standards side. A common standard for how OT security ends up designed and assessed is what makes risk assessable. And once risk can be assessed, it can be quantified, mitigated and transferred. That’s the chain: ISA/IEC 62443 gives the industry a shared language for control. Our platform turns that control state into a financial number a board can govern by and an underwriter can price against. Joining ISAGCA puts us alongside the organizations building that foundation. Our mission is to make industrial cyber risk quantifiable for boards, investors and the risk transfer market – and standards are what make that possible at scale.”

